Resultados: 8

Cost effectiveness analysis of plasma genotyping versus tumor genotyping in detection of advanced non-small-cell lung cancer with epidermal growth factor receptor and T790M mutation under the Brazilian private healthcare system perspective

Objective: Comparing the costs and effectiveness of plasma genotyping versus tumor genotyping for detecting the T790M mutation in advanced non-small cell lung cancer (NSCLC) with a mutation in the epidermal growth factor receptor (EGFR) and that progressed after use of an EGFR tyrosine kinase inhibitor (...

Treatment patterns of Hodgkin’s lymphoma in Brazil: experts’ perspective

Background: Hodgkin’s Lymphoma (HL) is a curable type of cancer, with a wide variety of therapies, especially for refractory/relapsing cases. Therefore, the study aims to explore the treatment patterns used in the management of HL patients in Brazil. Methods: A survey was developed to explore the treat...

Unmet needs in multiple myeloma in Brazil from physicians’ perspective – barriers in quality of life and disease management

Objective: There is an increasing trend of the overall survival rates of multiple myeloma (MM) patients over the years, increasing the necessity to improve their quality of life and attenuate unmet medical needs. Therefore, this study aims to explore and describe unmet medical needs and barriers in Brazi...

Hodgkin’s lymphoma unmet medical needs in Brazil: experts’ perspective

Background: In 2016, Hodgkin’s Lymphoma (HL) was responsible for 2,470 new cases in Brazil and, despite recent scientific advances, there are unmet medical needs that affects patients’ outcome. Therefore, we aimed to explore the unmet medical needs in the management of HL patients in Brazil, based on...

Cost-effectiveness and budgetary impact of lipegfilgrastim for the reduction of chemotherapy-induced neutropenia in Brazil

Background: Granulocyte-colony stimulating factors (G-CSFs) reduce the risk of chemotherapy-induced neutropenia. Lipegfilgrastim is a long-acting, once-per-cycle G-CSF, while Brazil’s standard of care is short-acting filgrastim. A cost-effectiveness and budget impact analysis of lipegfilgrastim was con...

New treatment approaches for relapsing/refractory Hodgkin’s lymphoma: An overview of the Brazilian scenario

Hodgkin’s lymphoma (HL) is a B-cell malignancy with a classical bimodal distribution with incidence peaking in the third and sixth decades of life. The purpose of this review is to describe the current unmet medical need for relapsing/refractory HL and the main data of emerging treatments, including br...

The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

J Vasc Surg; 67 (1), 2018
BACKGROUND: Decision-making related to the care of patients with an abdominal aortic aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient-specific factors influence anticipated life expectancy, operative risk, and need to intervene. Careful attention to the choice of op...

Economic fluctuations during pregnancy and smoking onset among adolescents in brazil: evidence from the 2012 national survey of school health

In this paper, we aim to investigate the potential relationship between smoking onset among nine-grade Brazilian students and economic fluctuations during their life in utero. Using data about smoking behavior from the 2012 National Survey of School Health and the unemployment rate as a proxy for economi...

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